Our data demonstrated that XRCC1 positive expression was significantly related to lymph node metastasis, invasion, and poor prognosis, which was consistent with previous studies (Ang et al., 2011; Abdel-Fatah et al., 2013; Mian et al., 2016). The gene discussed is XRCC1; the disease is metastatic malignant neoplasm in the lymph nodes.