AR and Familial prostate cancer: These are the top-scoring signaling pathways based on the gene enrichment distribution, which emphasizes that the DEGs from human sorted B-cells are triggered via oxidative stress and ROS-induced cellular signaling (Figure 6A), chemotaxis and lysophosphatidic acid signaling via GPCRs (Figure 6B), and androgen receptor activation and downstream signaling in prostate cancer (Figure 6C).