ELANE and neoplasm: CBC: complete blood count; CM: conditioned media; CRD: carbohydrate recognitiondomain; ECM: extracellular matrix; FBS: fetal bovine serum; FSC: forwardscatter; MMPs: metalloproteinases; MPO: myeloperoxidase; NB: neuroblastoma; NE:neutrophil elastase; PBMC: peripheral blood mononuclear cells; PMN:polymorphonuclear neutrophils; RBC: red blood cells; SSC: side scatter; SWH:scratch wound healing; TME: tumor microenvironment.