Two studies based on CFTR (OMIM# 602421) variation analysis by Sher-e-Kashmir Institute of Medical Sciences, Kashmir in the Kashmiri population suspected with Cystic Fibrosis (OMIM# 219700) has revealed disease’s association with highly frequent CFTR. ΔF508 (c.1521_1523delCTT; p.Phe508del) and CFTR. 3,849+10 kb C > T variations (Kawoosa et al., 2014; Pandith et al., 2015). The gene discussed is CFTR; the disease is cystic fibrosis.