Prominent DEGs were identified in each stage, for instance, the downregulation of CYP26A1, MTRNR2L1, ELOA and upregulation of FAM53A, PPP1R35, BLM at GV, MI, MII stages in PCOS oocytes, respectively (Figure 3B). This evidence concerns the gene CYP26A1 and polycystic ovary syndrome.