Although genetic variants in ATM have been associated with various cancers (Barrett et al., 2011; Helgason et al., 2015; Ransohoff et al., 2017; Scelo et al., 2017), only one genetic variant in ATM, rs227080, was genome-wide significantly associated with LTL in a Singaporean Chinese population (Dorajoo et al., 2019). This evidence concerns the gene ATM and cancer.