MALT1 and lymphoma: The discovery of MALT1 paracaspase activity triggered an intense research interest, providing a novel paradigm to dampen pathological hyperactivity of CBM pathways, which MALT1 contributes to by proteolytic cleavage of several key regulators among which A20, CYLD, RelB, and BCL10 (9), be it in lymphoma settings (10, 11) or in autoimmune/auto-inflammatory disorders (12).