IL17A and neoplasm: The results of the metagenomic pathway function prediction show that the tumor signaling pathway, antigen recognition and presentation, Th17 cell differentiation, IL-17 secretion, estrogen signaling pathway, pyrimidine metabolism, nucleic acid shearing and repair are related to the poor efficacy of immunotherapy; and the biosynthesis of steroid hormones, mannose, phenylpropane, beet red, carotene, and the like is related to better therapeutic effects.