Overall, 53 potential candidate genes were identified to be associated with CAD (Supplementary Table S4), and 13 candidate genes (CARF, FAM177B, GGCX, FAM117B, TDRD10, SWAP70, SUSD2, RP1-257A7.5, VAMP5, SPECC1L, RGL3, KANK2, SLC22A1) can be considered as novel genes. This evidence concerns the gene SPECC1L and coronary artery disorder.