Intriguingly, denervation (DEN), and concomintant treatment of dexamethason (DEX), a synthetic glucocorticoid, produces characteristic pathologic feature of severe muscle atrophy, and preferential myosin depletion, although DEX treatment alone elicites muscle atrophy without loss of myosin (Rouleau et al., 1987; Mozaffar et al., 2007; Yamada et al., 2018, 2019). This evidence concerns the gene MYH14 and Atrophy.