These features are distinct from non‐cytotoxic T‐cell lymphomas, which are exemplified by angioimmunoblastic T‐cell lymphoma, adult T‐cell leukemia/lymphoma, mycosis fungoides, etc. 17They generally share an aggressive clinical course due to resistance to ordinal multi‐agent chemotherapy, although several unique indolent cytotoxic diseases have been identified over the last decade, including primary cutaneous acral CD8+ T‐cell lymphoma,5 lymphomatoid gastropathy,25 NK‐cell enteropathy26 and an enteropathy‐like indolent NK‐cell proliferation of the female genital tract.27 This evidence concerns the gene CD8A and lymphoma.