They were related to metabolic pathways (26.23%), ribosomes (8.87%), protein processing in the endoplasmic reticulum (6.17%), endocytosis (5.63%), lysosomes (5.29%), Huntington disease (5.17%), pathways in cancer (4.88%), starch and sucrose metabolism (4.50%), the PI3K-Akt signalling pathway (4.45%), phagosomes (4.26%) and other pathways (24.5%) (Fig. 6). The gene discussed is AKT1; the disease is juvenile Huntington disease.