As LOXL1 showed more significance in glioma progression, we tested LOXL1 expression in U87 and LN18 cells (Fig. 1f, upper panel), and then used U87 cells as the parent cell line for forced LOXL1 expression (U87-LOXL1) and LN18 cells for LOXL1 knockdown (LN18-shLOXL1). Here, LOXL1 is linked to central nervous system cancer.