An increased expression of HB marker keratin 19 (K19) has been observed in human squamous cell carcinomas (SCCs) (Chen et al, 2008), whereas basal cell carcinomas and trichoblastomas were shown to up-regulate the expression of the HB marker keratin 15 (K15) (Kim et al, 2016). The gene discussed is KRT15; the disease is squamous cell carcinoma.