ITGA3 and hydrops fetalis: This was expected, as hair cycle was not altered in K14 Itga3 KO mice of similar age (Sachs et al, 2012), although the loss of integrin α3β1 has been shown to affect HF maintenance and morphology in mice, bred onto C57Bl/6 background (Conti et al, 2003; Sachs et al, 2012).