ITGA3 and papilloma: To this end, we performed RNA sequencing of GFP-positive keratinocytes isolated from the skin of K19 Itga3 KO and WT mice during the initiation stage of tumorigenesis induced by short-term DMBA/TPA treatment, which has been shown to be sufficient for the outgrowth of papillomas (Diwan et al, 1985; Hennings et al, 1985).