The administration of UC-MSCs has also been shown to reduce collagen concentrations in the lung and to inhibit the expression of transforming growth factor-beta (TGF-β), interferon-gamma (IFN-γ), macrophage migratory inhibitory factor and tumor necrosis factor-alpha (TNF-α) in a murine model of bleomycin-induced acute lung injury [97]. This evidence concerns the gene TNF and acute lung injury.