RNY4P25 and melanoma: The authors also related the presence of these Y RNA with the disease stage, finding that five of them (namely: RNY3P1, RNY4P1, RNY4P6, RNY4P18, and RNY4P25) are differentially expressed; RNY3P1, RNY4P1, and RNY4P25 fragments show a specific enrichment in stage 0 samples, compared to control samples or stage I/II samples (validation cohort: 22 controls and 58 melanoma patients samples).