CRP and neoplasm: We furthermore showed that a CRS incorporating CRP ≥0.2 mg/dL, tumor-size ≥3 cm, and the presence of metastases enables preoperative stratification by the prediction of postoperative 90-day morbidity and mortality, unfavorable oncological parameters (grading, T category, and lymph node involvement), rate of recurrence, and poor long-term survival.