Univariable analysis of preoperative factors and OS after surgery in the ASSO cohort (Figure 2 and Table 2) showed a significant association with CRP ≥0.2 mg/dL (HR 4.13; 95%CI 1.46–11.7), metastases (HR: 3.32; 95%CI 1.64–6.71), tumor-size ≥3 cm (HR 2.41; 95%CI 1.21–4.82), symptoms other than pain (HR 2.18; 95%CI 1.03–4.62), and age (HR: 1.59 per 10 years; 95%CI 1.18–2.13). Here, CRP is linked to neoplasm.