Indeed, various acute and chronic inflammatory diseases, including gastritis, colitis, Crohn’s disease, ulcerative colitis, inflammatory bowel disease, and Hashimoto’s thyroiditis (data not shown), which are major causes of cancer in the colon, stomach, and thyroid, respectively, exhibited elevated protein and transcription levels of ICMT and Ras (Figure 1). Here, ICMT is linked to Hashimoto thyroiditis.