SOD1 and amyotrophic lateral sclerosis: Wild-type SOD1 (SOD1WT) is not commonly associated with aspects of neurodegeneration including in ALS, although upon post-translational modification such as iper-oxidation, even if noninheritable, studies suggest the possibility of its additional toxic role in sALS [87,88], which confers with the existing literature on the prion-like potential of SOD1, both wild and mutant [87,89,90,91].