However, it must also be noted that the examined literature for each protein in relation to miRNA dysregulation has often led to inconclusive evidence about specific miRNAs in ALS, instead depicting a wide spectrum of certain affected miRNAs, despite no evident connection between them; notably, research has been specific to mouse models or fALS patients depicting exclusive genetic mutation, whether it be in TARDBP, FUS, or SOD1. This evidence concerns the gene SOD1 and amyotrophic lateral sclerosis.