SOD1 and amyotrophic lateral sclerosis: Interestingly, as miRNAs do regulate various genes involved in oxidative stress response, and as the converse also proves true, it is important to consider the strength of interrelationship between miRNA dysregulation and ALS pathogenesis, especially as oxidative stress is so strongly related to both SOD1 and other parts of pathogenesis, potentially leading to other processes of degeneration, despite often being examined in separation to RNA dysregulation [103].