In the final model (Table 5), the predictors for severe leptospirosis included abnormal pulmonary sounds (p = 0.001,OR= 3.07, 95% CI = 1.58–6.0), hepatomegaly (p = 0.04, OR = 7.14, 95% CI = 1.10–45.98), hypotension (p = 0.03, OR = 2.16, 95% CI = 1.08–4.34), WBC (p = 0.001, OR = 2.12, 95% CI = 1.37–3.29), hematocrit (p = 0.001, OR = 2.33, 95% CI = 1.43–3.81), and SGPT ALT (p = 0.001, OR = 2.12, 95% CI =1.36–3.30). This evidence concerns the gene GPT and leptospirosis.