The results showed that the silenced GNL3L reduced the tumor volume significantly in the LoVo cell group compared with that of the control group (Figure 7F–H), and we further confirmed GNL3L expression using Western blotting and immunohistochemistry (Figure 7I,J) and NF-κB expression using IHC (Figure 7K). The gene discussed is NFKB1; the disease is neoplasm.