BAP1 and Familial prostate cancer: In order to investigate the positive role of BAP1 in the development of prostatecancer, we assessed the BAP1 levels in several prostate cancer cell lines.Notably, the expression of BAP1 protein was high in tumorigenic and metastaticcell lines, including RWPE2, LNCaP, PC3, and DU145, but was low in normalprostate cell line RWPE1 (Figure 1D).