The rs114598080 SNP, located in a CTCF binding site (ENSR00000262841) 15.6 kb upstream of the HLA-C gene, gave a univariate p-value of 8.8x10-13 in the combined analysis, with an OR for developing leprosy for AG vs. GG (or AA vs. AG) of 1.47 [1.46–1.48]. This evidence concerns the gene HLA-C and leprosy.