NRGN and Alzheimer disease: The CSF Ng levels also related to the decline of ADNI_MEM (β = -0.05, P<0.001 and β = -0.07, P = 0.044) and ADNI_EF (β = -0.04, P = 0.013 and β = -0.10, P = 0.008) scores in subjects with MCI and AD (Table 2).