Despite very low numbers, variants found within two of the enhancers identified, intronic to CD69 and UBASH3A, were found to be associated with changes in histone marks and differential gene expression of CD69 and UBASH3A. Similarly, an alternative study using T-helper cells and B cells from 344 untreated RA patients, discovered eQTLs for a total of 14 genes at 10 RA loci, roughly half of which were specific to either cell type (37). Here, CD69 is linked to rheumatoid arthritis.