To verify whether miR-26a-5p and CTGF regulate TLR signal pathway in the mouse alveolar macrophage severe pneumonia model, qRT-PCR and Western blot were used to detect the expression level of TLR2, TLR4 and NF-κB in each group of cells (Figures 6 and 7). The gene discussed is TLR2; the disease is pneumonia.