Immunohistochemical Bcl-2 assessment of liver sections of rats with age-related hepatic steatosis showed a significant reduction in the Bcl-2 content; however, the liver sections isolated from rats treated BDS (450 mg/kg), CDS (30 mg/kg), and ZH (250 μg/kg) expressed high degree of positivity revealing improvement. The gene discussed is BCL2; the disease is fatty liver disease.