KIR3DL1 and myelodysplastic syndrome: However, the frequencies of strong inhibitory ligand HLA-Bw4 and KIR3DL1-HLA-Bw4 combination were significantly higher in healthy controls than those in MDS patients, respectively (HLA-Bw4: 73.42% vs. 62.34%, P = 0.038; KIR3DL1-HLA-Bw4: 70.87% vs. 59.74%, P = 0.043).