The PTEN gene is associated with the PTEN hamartoma tumor syndrome including the overlapping Cowden (CS) and Bannayan‐Riley‐Ruvalcaba syndromes, the adult‐onset Lhermitte‐Duclos disease, and autism spectrum disorders with macrocephaly (Pilarski, 2019; Tan et al., 2012). The gene discussed is PTEN; the disease is Adult onset.