The resulting network models showed specific differences in YWHAZ amplification in BRCA, PIK3CB amplification in CESC, PIK3R1 mutation in UCEC, and downregulation of XRCC6, NMT1 and CASP3 in OV, which suggests that the BCL2 family protein network can be used to identify different types of gynaecologic cancer. This evidence concerns the gene CASP3 and cervical squamous cell carcinoma.