PTEN and Familial prostate cancer: Most deletions in prostate cancer are either linked to an ERG-positive (3p, 8p, PTEN, 12q, 16q, 17q) [21, 24, 25, 28, 29, 49] or ERG-negative status (5q, 6q, 13q, 18q) [6, 20, 23, 26].