In motor axonal study of seropositive patients, anti‐SSA level is correlated with hyperpolarized I/V slope (Rho=−0.46, P < 0.05), while duration of dry eyes was correlated with SDTC (Rho = 0.45, P < 0.05), and superexcitability (R = 0.41, P < 0.05); duration of dry mouth was correlated with TEd(40–60 ms) (R = 0.40, P < 0.05). The gene discussed is CALR; the disease is dry eye syndrome.