KLRK1 and infection: Murine poly(I:C)-treated intestinal T-IEL kill primary poly(I:C)-treated IEC in vitro and in vivo dependent on NKG2D/Rae-1 interactions.58 Infection of mice with Salmonella16 and E. moshkovskii59 also triggers NKG2D-mediated cytotoxicity of T-IEL against epithelial cells.