The generally high but variable expression of SOX6 was also observed in EwS cell line models compared to cell lines of three other pediatric cancer types including osteosarcoma (U2OS and SAOS-2), neuroblastoma (TGW and SK-N-AS) and rhabdomyosarcoma (Rh36 and Rh4) (Supplementary Fig. 1). This evidence concerns the gene SOX6 and neuroblastoma.