CD8A and Epstein-Barr virus infection: Conversely, for a donor experiencing IM, a profound clinical manifestation of primary EBV infection (see Supplemental Table 1), EBV tetr+ cells comprised only ~4% of CD8+ PBMC (i.e. <4-fold increase over the HD), but >75% of these were in G1 and ~20% in S-G2/M.