The remaining seven genes and their three associated conditions — HBOC (BRCA1/2), Lynch syndrome (MLH1, MSH2, MSH6, PMS2), and MUTYH-associated polyposis (MUTYH) — do not typically lead to pediatric onset of disease [10, 13], and thus, recommended surveillance and risk-reducing actions are postponed until adulthood [14, 15]. The gene discussed is MSH2; the disease is Lynch syndrome.