Specific to a clinically actionable, adult-onset condition, one study found that, female adolescents (age 11–19 years) from BRCA1/2 families did not differ in their general psychosocial adjustment as compared to girls from breast cancer families without a BRCA1/2 pathogenic/likely pathogenic variant and peers without breast cancer in their family [43]. The gene discussed is BRCA1; the disease is breast cancer.