So far, polymorphism about age-related maculopathy susceptibility 2 (AMRS2) rs10490924, complement factor H (CFH), complement 2 (C2)/complement factor H (CFB), complement component C3 and apolipoprotein E (APOE) haplotypes have been demonstrated as associated factors with susceptibility to AMD [14–18]. The gene discussed is CFH; the disease is age-related macular degeneration.