The analysis of the plasma samples of GBM patients (P4–P9) with no gene fusions reported in the MGH Solid Fusion Assay revealed fusion transcripts in P4 (TMEM91-TAL1, CRTC1-ABHD12), P8 (TMEM91-TAL1) and P9 (RAB7A-FOXP1). Here, TMEM91 is linked to glioblastoma.