Even though so far no clear evidence demonstrates that the involvement of CD1d-lipid antigens in tumor cell recognition by γδ T cells; however, CD1d is found to be expressed on multiple cancers, such as lymphomas, early myeloma, myeloid leukemias, medulloblastoma, and prostate cancers [60,61,62,63]. This evidence concerns the gene CD1D and plasma cell myeloma.