SOAT1 and metabolic dysfunction-associated steatohepatitis: In the current study, we used bioinformatics to screen out the differentially expressed mRNAs and miRNAs in liver tissues of NASH patients, and verified the effect of miR-142-5p on TSLP and JAK-STAT signaling pathway and its role in NASH by constructing a NASH mice model, in order to find a new target for the treatment of NASH.