Further dual luciferase reporter experiment revealed that the target gene of miR-142-5p was TSLP, so we believed that miR-142-5p might play a role in the occurrence of NASH by affecting the expression of TSLP. Similarly, a previous study showed that miR-142-5p can affect the expression of fibrotic genes, and fibrosis is one of the important causes of NASH [9]. This evidence concerns the gene TSLP and metabolic dysfunction-associated steatohepatitis.