GATA3 and chlamydia trachomatis infectious disease: The increased expression of GATA-3 and IL-4 secretion of our study favors the dominance of Th2 cells, reflecting the switching of IFN-γ production by Th1 to IL-4 production by Th2 that probably subsequently result in the pathological development of chlamydia genital infection [13, 18].