Differentially expressed genes related to osteosarcoma were identified using the microarray dataset of GSE41445 from the GEO database, which revealed increased lncRNA PGM5‐AS1 expression in osteosarcoma samples through differential analysis of the gene expression in three normal samples and three osteosarcoma samples (Fig. 1A). The gene discussed is PGM5; the disease is osteosarcoma.