Furthermore, Zhang et al. (2018a, 2018b,2018a, 2018b) confirmed that the depleting the expression of small nucleolar RNA host gene 16 led to increased miR‐140‐5p levels, thus downregulating ZEB1 and thereby dampening esophageal squamous cell carcinoma cell proliferation, migration, and EMT. Here, ZEB1 is linked to esophageal squamous cell carcinoma.