TP53 and central nervous system cancer: Since the expression of miR‐10b was found to be up‐regulated and be closely related to the poor prognosis of glioma,26, 27, 28 researchers have discovered that miR‐10b may be involved in tumorigenesis by activating the p53 pathway29 and induced glioma cell invasion by miR‐10b/HOXD10/MMP‐14/uPAR signalling pathway.30