However, a recent study found that the inhibition of miR-22-3p in vivo resulted in decreased IgG deposition in the kidney, decreased STAT1 phosphorylation and decreased kidney disease, in a mouse model of systemic lupus erythematosus (SLE) (doi: https://doi.org/10.1101/512848). The gene discussed is STAT1; the disease is systemic lupus erythematosus.