HNF4A and neuroblastoma: At last, the expression levels of E-cadherin, N-cadherin, and Vimentin were used to represent the level of EMT in NB cells, Western blot analysis disclosed that SNHG16 detetion could retard EMT, while the curbed effect of SNHG16 deficiency on EMT was regained by up-regulation of HNF4α in vitro (Figure 5G–J).