Giannotta et al. reported reactivity to sulphatide in only 1% of CIDP patients.55 Interestingly, a recent report highlighted an elevated frequency of at least one IgM autoAb to GM1, GD1b and sulphatide in patients suffering from CIDP.27 Here, patients with autoAbs to sulphatide were younger and demonstrated typical manifestations of clinical symptoms characteristic for CIDP. Here, CD40LG is linked to chronic inflammatory demyelinating polyradiculoneuropathy.