Moreover, upregulated plasma miRNA target genes associated with B cell receptor (BCR) (EGR3) and T cell receptor (TCR) (MLLT3, DUSP3, DUSP5, DUSP7, DUSP8, DUSP16, NR4A3, CD34, CD58, CD8A, CD247, and CD276) adaptive immune responses implicated in psoriasis were identified. Here, EGR3 is linked to psoriasis.