Moreover, upregulated plasma miRNA target genes associated with B cell receptor (BCR) (EGR3) and T cell receptor (TCR) (MLLT3, DUSP3, DUSP5, DUSP7, DUSP8, DUSP16, NR4A3, CD34, CD58, CD8A, CD247, and CD276) adaptive immune responses implicated in psoriasis were identified. This evidence concerns the gene CD58 and psoriasis.