CD274 and esophageal adenocarcinoma: Most interestingly however, low CD8+ lymphocyte infiltration coupled with low PD-1/PD-L1 scores (PD-1/PD-L1/CD8 low) also significantly correlated with poor OS in gastric and esophageal adenocarcinomas (HR;0.53; 95%CI:0.29–0.96; P = 0.037).