Lu et al. (2014) reported that NMN improved energy activity and survival rate in an in vitro model of Parkinson’s disease. Fang et al. (2016) also demonstrated that NR and NMN were able to normalize neuromuscular function and memory by regulation of mitophagy and enhancement of DNA repair in mice and worm models of ataxia-telangiectasia (AT), an autosomal recessive disease with progressive neurodegeneration. The gene discussed is NTS; the disease is ataxia telangiectasia.