Since normal and tumor ceRNA networks within each subtype share the same number of samples and thus would not suffer from this bias (Altay et al., 2011; Chen H. et al., 2018; Park et al., 2018b; Dalgiç et al., 2019), we applied the subtype-specific cutoffs (0.68 for ER- and 0.6 for ER+) to build the tumor ceRNA networks in each subtype. This evidence concerns the gene ESR1 and neoplasm.