Since the regulation of the cell cycle, G1- and S-phase and their transition ratio, is especially crucial for ER+ tumor's proliferation [reviewed in (Foster et al., 2002)], it is interesting that the cell cycle regulation pathways for various phases (G1/S or G2/M) of various mediators (estrogen or cyclins) are enriched with 144 ER+ HK ceRNA partners. The gene discussed is ESR1; the disease is neoplasm.